Synthetic Nanoelectronic Probes for Biological Cells and Tissues

Synthetic nanoelectronic probes for biological cells and tissues.

Research at the interface between nanoscience and biology could yield breakthroughs in fundamental science and lead to revolutionary technologies. In this review, we focus on the interfaces between nanoelectronics and biology. First, we discuss nanoscale field effect transistors (nanoFETs) as probes to study cellular systems; specifically, we describe the development of nanoFETs that are compar...

Macroporous nanowire nanoelectronic scaffolds for synthetic tissues.

The development of three-dimensional (3D) synthetic biomaterials as structural and bioactive scaffolds is central to fields ranging from cellular biophysics to regenerative medicine. As of yet, these scaffolds cannot electrically probe the physicochemical and biological microenvironments throughout their 3D and macroporous interior, although this capability could have a marked impact in both el...

Synthetic probes for the study of biological function

From its beginnings, organic chemistry has been a partner to biology, often crossing the artificial boundary between the sciences to the benefit of both disciplines. This is even reflected in the use of the adjective “organic” to refer to the chemistry of carbon. As the field has matured, it has continued to address matters of structure and synthesis to increasingly encompass the grand challeng...

Methods and Devices for Cryopreservation of Biological Cells and Tissues

Ultraflexible nanoelectronic probes form reliable, glial scar–free neural integration

Implanted brain electrodes construct the only means to electrically interface with individual neurons in vivo, but their recording efficacy and biocompatibility pose limitations on scientific and clinical applications. We showed that nanoelectronic thread (NET) electrodes with subcellular dimensions, ultraflexibility, and cellular surgical footprints form reliable, glial scar-free neural integr...